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This file contains 32,881 calculated GO-Pfam associations.
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Families of related proteins and their different functions may be described systematically using common classifications and ontologies such as Pfam and GO, for example. However, many proteins consist of multiple domains, and each domain, or some combination of domains, can be responsible for a particular molecular function. Therefore, identifying which domains should be associated with a specific function is a non-trivial task. We describe “GODomainMiner” for associating GO terms with protein domains. We used GODomainMiner to predict GO-domain associations between each of the three GO namespaces (MF, BP, CC) and the Pfam, SCOP, and CATH domain classifications.